Multidrug therapy protocols
SOGC/GOC Clinical Guideline #408, January 2021
| Protocol | Drug, dosage and route of administration | Administration |
|---|---|---|
| TP/TE | Paclitaxel 135 mg/m2 IV infusion | D1 |
| Cisplatin 60 mg/m2 IV infusion | D1 | |
| Paclitaxel 135 mg/m2 IV infusion | D15 | |
| Etoposide 150 mg/m2 IV infusion | D15 | |
| ECI | Ifosfamide 5000 mg/m2 IV infusion | D2 |
| Carboplatin AUC 5 IV infusion | D2 | |
| Etoposide 100 mg/m2 IV infusion | D1 - D3 | |
| BEP | Bleomycin 30 units IV | D1, D8, D15 |
| Etoposide 100 mg/m2 IV infusion | D1 - D5 | |
| Cisplatin 20 mg/m2 IV infusion | D1 - D5 | |
| Low dose induction | Etoposide 100 mg/m2 IV infusion | J1 - J2 Repeat every week for 1-3 weeks. |
| Cisplatin 20 mg/m2 IV infusion | J1 - J2 Repeat every week for 1-3 weeks. |
2021. Guideline No. 408: Management of Gestational Trophoblastic Diseases. Eiriksson L, Dean E, Sebastianelli A, Salvador S, Comeau R, Jang JH, Bouchard-Fortier G, Osborne R, Sauthier Ph. J Obstet Gynaecol Can;43(1):91-105.
Modified on 12/23/2023