Placental site nodule (PSN) | paucicellular, hyaline material | no mitotic activity |
Exaggerated placental site (EPS) | abundant intermediate trophoblasts - between muscle | no mitotic activity |
Placental site trophoblastic tumor (PSTT) | abundant cytoplasm - not clear, dyscohesive | +/- multinucleation |
Epithelioid trophoblastic tumor (ETT) | nests of cells in hyaline stroma | eosinophilic cytoplasm, central nucleus |
Choriocarcinoma | polygonal cells with clear cytoplasm (cytotrophoblasts) | multinucleated cells with smudged nuclei (syncytiotrophoblasts), no chorionic villi |